# Master Thesis: Targeting Social Behavior Networks in Mental Disorders: A Meta-Analysis of Oxytocin’s Neural Effects
# Author: Hannah Baulig
# Year: 2025
# Institution: Technical University Dresden
# Generated by: Hannah Baulig
# Advisors: Dr. Lara Maliske, Dr. Evelyn Muschter
# Description: Coordinate-based meta-analysis (CBMA) of oxytocin-related fMRI studies using SDM-PSI. Includes whole-brain and ROI peak coordinates, metadata tables, and full SDM-PSI outputs for main analyses and subgroup analyses


This repository contains a coordinate-based meta-analysis (CBMA) of oxytocin effects on brain activity across published fMRI studies.  
Note: This dataset does not include raw neuroimaging images. All analyses are based on peak coordinates reported in published studies.

For more detailed information about each subfolder, please see the README files in `META/`, `SDM/`, and `Scripts/`.


## Folder Structure

BIDS/
├ META/
├ SDM/
└ Scripts/

### **META/**
Contains all study-level metadata, extracted peak coordinates (ROI + whole-brain), and supplementary documents for verification.

### **SDM/**
Contains all SDM-PSI 6.23beta outputs, including:
- main meta-analysis  
- subgroup analyses  
- NIfTI maps  
- plots  
- extracted effect sizes  
- SDM tables  

### **Scripts/**
MATLAB scripts used to:
- generate META files  
- convert coordinates  
- create SDM tables  

---

## Methods Summary

- **Software:** SDM-PSI 6.23beta (Radua et al., 2024)  
- **Environment:** MATLAB R2023b  
- **Meta-analysis:** Random-effects CBMA  
- **Imputations:** 50  
- **Permutations:** 500  
- **Thresholds:** p = .001 uncorrected; p = .05 FWE-corrected  
- **Additional analyses:** subgroup analyses, meta-regressions, linear models  

---

## Citation

Please cite:
- SDM-PSI publications:
  - Radua et al., 2024 – [https://www.sdmproject.com](https://www.sdmproject.com)
  - Albajes-Eizagirre et al., 2019 – [https://doi.org/10.3791/59841]
- Master Thesis by Hannah Baulig: "Targeting Social Behavior Networks in Mental Disorders: A Meta-Analysis of Oxytocin’s Neural Effects" (2025) 

---

## License
This dataset is released under a CC-BY 4.0 license. Users are free to reuse and adapt the data, provided they cite the thesis and relevant SDM-PSI publications.