This data deposit contains all the raw data of the manuscript to the paper "The role of alveolar epithelial junctions in early lung injury and COVID-19-induced fibrosis". The data is sorted by 3.1 to 3.4 corresponding to the headlines of the "Results" Section of the manuscript. 3.1 and 3.2 contain the raw microscopic pictures with corresponding negative controls devided by pathologic groups and the mRNA analysis data. 3.3 contains the raw microscopic pictures with corresponding negative controls named with different Treatments and the Western blots. 3.4 contains the raw microscopic pictures with corresponding negative controls of fluorescence and light microscopy.