Behavioral data from the Individuality paradigm

Kempermann, Gerd

Behavioral data from the Individuality paradigm

Type of the data datacite.resourceTypeGeneral	Dataset
Total size of the dataset datacite.size	396175979
Author dc.contributor.author	Kempermann, Gerd
Upload date dc.date.accessioned	2025-12-08T13:06:49Z
Publication date dc.date.available	2025-12-08T13:06:49Z
Data of data creation dc.date.created	2020
Publication date dc.date.issued	2025-12-08
Abstract of the dataset dc.description.abstract	The data sets contain pre-processed raw data of antenna contacts of mice cohorts living within the Individuality set-up (ColonyRack), i.e. 70 connected cages that provide one large enriched environment. The data sets contain raw and processed data from antenna contacts that the mice made across the experimental period. The R package 'ColonyTrack' (https://rupertoverall.net/ColonyTrack/) was used to generate the data, which are presented in the compressed RData format. The two files contain the data for all individual mice in the experiments of both genotypes, Cyclin D2 knockouts and wildtypes with all spatial and temporal coordinates along with the mouse IDs.
Public reference to this page dc.identifier.uri	https://opara.zih.tu-dresden.de/handle/123456789/1867
Public reference to this page dc.identifier.uri	https://doi.org/10.25532/OPARA-1024
Publisher dc.publisher	Technische Universität Dresden
Licence dc.rights	Attribution-NonCommercial 4.0 International	en
URI of the licence text dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/
Specification of the discipline(s) dc.subject.classification	2
Title of the dataset dc.title	Behavioral data from the Individuality paradigm
Research instruments opara.descriptionInstrument	ColonyRack system (costum-built by Phenosys Berlin). The system is described in detail in several publications of the group, including Kempermann et al. (2022) DOI: 10.1016/j.nbd.2022.105916
Underlying research object opara.descriptionObject.Organism	Mice
Software opara.descriptionSoftware.ResourceProduction	ColonyTrack (R package)
Project abstract opara.project.description	As complex individualized behaviors in mice arise even when genes and environment are held constant, emerging social group structures should also depend on individual behavior. Adult neurogenesis drives individual behavior and is involved in certain social behaviors. Would thus the emergence of social structure depend on adult-born neurons? To answer this questions, we co-housed cohorts of mice with intact and genetically diminished adult hippocampal neurogenesis in a large-scale automated tracking system for three months and analyzed the development of social behaviors over time. Not only did female mice develop stable hierarchies, we also found that, despite forming a functioning mouse society, their dominance behavior increasingly diverged over time. Specifically, neurogenesis-deficient mice showcased a greater increase in hierarchical behavior throughout the experiment. Within the social behaviors, mice showed no genotype-based preference, indicating intrinsic causes for behavioral differences. In mice with intact neurogenesis, social rank was positively correlated with adult hippocampal neurogenesis. Nevertheless, neurogenesis-deficient mice occupied higher ranks in the emerging hierarchy than their wild-type cohabitants, while displaying less individualization for this trait. The observed insistence on dominance might therefore reflect inflexible social strategies. Thus, social intelligence and flexibility, enabled by adult-born neurons, promote social adaptability, egality, and flatter hierarchies.
Funding Acknowledgement opara.project.fundingAcknowledgement	Volkswagenstiftung Project "The Mouse in the Supermarket"
Project title opara.project.title	New Neurons Flatten Social Hierarchies