Research data for: "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets"

Contributing person
datacite.contributor.ProjectMember

René Brands

Contributing person
datacite.contributor.ProjectMember

Jens Bartsch

Contributing person
datacite.contributor.Supervisor

Urs Alexander Peuker

Contributing person
datacite.contributor.Supervisor

Volker Schmidt

Contributing person
datacite.contributor.Supervisor

Markus Thommes

Documentation of the data
datacite.description.TechnicalInfo

Micro-CT image data and segmented image data in tiff format can be easily opened and further processed with different software tools, for example, with the free image processing software of Fiji (ImageJ) or ilastik. Furthermore, the image data can be processed using numerical computing programs and their toolboxes like Matlab or various libraries (e.g. Scikit-Image, OpenCV) of the programming language Python.

References to related material
datacite.relatedItem.IsSupplementTo

Journal article with title "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets"

Description of the data
datacite.resourceType

1 micro-CT data set (16-bit raw tiff image stack after stitch scanning and reconstruction); 1 segmented (binary) data set of only active ingredient (16-bit tiff image stack after segmentation using 3D U-Net; downscaled); CT measurement and reconstruction parameters

Type of the data
datacite.resourceTypeGeneral

Dataset

Total size of the dataset
datacite.size

8221139795

Author
dc.contributor.author

Seyffer, Judith Miriam

Author
dc.contributor.author

Fuchs, Lukas

Upload date
dc.date.accessioned

2025-03-20T12:00:14Z

Publication date
dc.date.available

2025-03-20T12:00:14Z

Data of data creation
dc.date.created

2024-08

Publication date
dc.date.issued

2025-03-20

Abstract of the dataset
dc.description.abstract

The data set comprises the micro-CT data for the publication Brands et al. (2025). In a joint work within the 1st funding period of the SPP2364, the three-dimensional distribution of the active ingredient in pharmaceutical tablets is investigated using a segmented CT image data set of a tablet. The data published here contains the raw, reconstructed micro-CT image data after acquisition using the Zeiss Xradia Versa 510. Imaging was performed by stitching five individual, overlapping region of interest scans over the full width of the tablet. Additionally, the data set of the segmented active ingredient particles is included in a downscaled version. Further information can be found in the corresponding publication "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets".

Public reference to this page
dc.identifier.uri

https://opara.zih.tu-dresden.de/handle/123456789/1381

Public reference to this page
dc.identifier.uri

https://doi.org/10.25532/OPARA-797

Publisher
dc.publisher

Technische Universität Bergakademie Freiberg

Licence
dc.rights

Attribution 4.0 Internationalen

URI of the licence text
dc.rights.uri

http://creativecommons.org/licenses/by/4.0/

Specification of the discipline(s)
dc.subject.classification

4::41::402::402-01

Specification of the discipline(s)
dc.subject.classification

4::44::407::407-02

Specification of the discipline(s)
dc.subject.classification

4::43::405::405-06

Specification of the discipline(s)
dc.subject.classification

2::22::205::205-09

Title of the dataset
dc.title

Research data for: "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets"

Research instruments
opara.descriptionInstrument

X-ray microscope Zeiss Xradia Versa 510 (Carl Zeiss Microscopy GmbH, Oberkochen, Germany)

Underlying research object
opara.descriptionObject.PhysicalObject

Pharamceutical tablet

Software
opara.descriptionSoftware.ResourceProcessing

Zeiss Reconstructor

Software
opara.descriptionSoftware.ResourceProduction

Zeiss Scout-and-Scan

Project abstract
opara.project.description

The priority program 2364 funded by the German Research Foundation (DFG) investigates and tests methods for autonomous process control in particle technology. It integrates material and data flows with measurement technology, process dynamics, and control to create a closed-loop autonomous process. Initially, it focuses on controlling single unit operations before expanding to entire process chains. The program develops scientific tools—methods, algorithms, and models—for reliable process control and process transformation. It investigates multiphase processes involving solids and fluid particles across synthesis, handling, and formulation operations.

Public project website(s)
opara.project.publicReference

https://www.mvm.kit.edu/SPP2364_APP.php

Public project website(s)
opara.project.publicReference

https://www.dfg.de/de/aktuelles/neuigkeiten-themen/info-wissenschaft/2024/ifw-24-108

Project title
opara.project.title

SPP 2364 Autonomous Processes in Particle Technology
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