Research data for: "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets"
Contributing person | René Brands | |
Contributing person | Jens Bartsch | |
Contributing person | Urs Alexander Peuker | |
Contributing person | Volker Schmidt | |
Contributing person | Markus Thommes | |
Documentation of the data | Micro-CT image data and segmented image data in tiff format can be easily opened and further processed with different software tools, for example, with the free image processing software of Fiji (ImageJ) or ilastik. Furthermore, the image data can be processed using numerical computing programs and their toolboxes like Matlab or various libraries (e.g. Scikit-Image, OpenCV) of the programming language Python. | |
References to related material | Journal article with title "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets" | |
Description of the data | 1 micro-CT data set (16-bit raw tiff image stack after stitch scanning and reconstruction); 1 segmented (binary) data set of only active ingredient (16-bit tiff image stack after segmentation using 3D U-Net; downscaled); CT measurement and reconstruction parameters | |
Type of the data | Dataset | |
Total size of the dataset | 8221139795 | |
Author | Seyffer, Judith Miriam | |
Author | Fuchs, Lukas | |
Upload date | 2025-03-20T12:00:14Z | |
Publication date | 2025-03-20T12:00:14Z | |
Data of data creation | 2024-08 | |
Publication date | 2025-03-20 | |
Abstract of the dataset | The data set comprises the micro-CT data for the publication Brands et al. (2025). In a joint work within the 1st funding period of the SPP2364, the three-dimensional distribution of the active ingredient in pharmaceutical tablets is investigated using a segmented CT image data set of a tablet. The data published here contains the raw, reconstructed micro-CT image data after acquisition using the Zeiss Xradia Versa 510. Imaging was performed by stitching five individual, overlapping region of interest scans over the full width of the tablet. Additionally, the data set of the segmented active ingredient particles is included in a downscaled version. Further information can be found in the corresponding publication "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets". | |
Public reference to this page | https://opara.zih.tu-dresden.de/handle/123456789/1381 | |
Public reference to this page | https://doi.org/10.25532/OPARA-797 | |
Publisher | Technische Universität Bergakademie Freiberg | |
Licence | Attribution 4.0 International | en |
URI of the licence text | http://creativecommons.org/licenses/by/4.0/ | |
Specification of the discipline(s) | 4::41::402::402-01 | |
Specification of the discipline(s) | 4::44::407::407-02 | |
Specification of the discipline(s) | 4::43::405::405-06 | |
Specification of the discipline(s) | 2::22::205::205-09 | |
Title of the dataset | Research data for: "Penetration depth and effective sample size characterization of UV/Vis radiation into pharmaceutical tablets" | |
Research instruments | X-ray microscope Zeiss Xradia Versa 510 (Carl Zeiss Microscopy GmbH, Oberkochen, Germany) | |
Underlying research object | Pharamceutical tablet | |
Software | Zeiss Reconstructor | |
Software | Zeiss Scout-and-Scan | |
Project abstract | The priority program 2364 funded by the German Research Foundation (DFG) investigates and tests methods for autonomous process control in particle technology. It integrates material and data flows with measurement technology, process dynamics, and control to create a closed-loop autonomous process. Initially, it focuses on controlling single unit operations before expanding to entire process chains. The program develops scientific tools—methods, algorithms, and models—for reliable process control and process transformation. It investigates multiphase processes involving solids and fluid particles across synthesis, handling, and formulation operations. | |
Public project website(s) | https://www.mvm.kit.edu/SPP2364_APP.php | |
Public project website(s) | https://www.dfg.de/de/aktuelles/neuigkeiten-themen/info-wissenschaft/2024/ifw-24-108 | |
Project title | SPP 2364 Autonomous Processes in Particle Technology |
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